Antibody Analysis Kits

Assay solutions for IgG quantification and glycan analysis of antibodies and proteins

The IgG Quantification and Glycan Analysis kits enable increased efficiency in upstream process development efforts. The ability to measure both titers and glycan properties using the same high-throughput assay format saves time, lab space, and resources. Our easy-to-use assay technology is well-suited for applications including early clone screening, biosimilar production, cell line and bioprocess development, antibody and protein engineering, media optimization, and more.

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These assay solutions enable researchers to tightly monitor product qualities such as titers and glycosylation directly within their own cell culture labs, without having to outsource to different departments or companies. Samples can be measured directly from supernatant without lengthy sample preparation, and time to result is 2 hours or less.

Features and Benefits:

No-wash, bead-based assay format
Provides a low barrier of entry to easily quantifying IgG and analyzing glycan profiles by not requiring any special lab instrumentation
Speeds up screening processes with time to result of <2 hours
All assays take place in 384 well-plate format, to increase sample throughput. Entire plate does not have to be used at once, and can be stored for future use
Easily automatable workflow to further increase overall throughput

Conserves precious samples by utilizing much lower sample volume than traditional methods require (<10 uL of sample volume required)
Quantification kits cover a wide concentration range and are compatible with a wide variety of analytes, including: Fc-fusion proteins; human IgG; mouse IgG; Fab fragments
Glycan Analysis kits can screen for the following: core fucose; terminal galactose; terminal GlcNac; high mannose; sialic acid

PAIA Titer Assay Menu

For more information about PAIA titer assays please click here to download the product menu.

Assay Robotics

Automated assay development

Assay Robotics is a turn-key automated assay development service for pharma, biotech, and research centers. Our team of scientists and engineers helps companies develop and implement assays to run on new or existing liquid handling robots.

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Innovation via state-of-the-art assays is crucial in reducing the time and cost to bring pharma and biotech drug candidates through R&D and to market. However, development of these assays can take months, thus contributing to a major part of the drug development bottleneck. Automating assays is the key to managing the throughput, expensive reagent cost, accuracy, sensitivity, safety, and efficacy requirements. Assay Robotics is a turnkey automated assay development service to help companies develop and implement assays to run on liquid handling robots. Our goal is to help companies free up their schedules to spend more time working on experiments, and much less time spent learning to program and run assays on robotic instrumentation.

What does Assay Robotics assist with?

Assessment and selection of best fit liquid handling robot manufacturer and software, or utilization of customer’s existing platforms
Development of the assay(s) for automation, Including flexible assay design that allows companies to easily modify and adapt to future workloads and changes in a cost-effective manner
Programming and integrating assay(s) into the robot
Ensuring that project performance requirements, milestones, and timelines are met
Demonstrating that the new automated assay meets or exceeds specifications
Installation and implementation of the assay(s) at customer’s facility

Why partner with us for assay development?

No more need to dedicate 100% of your staff to a short-term project
Our team of engineers and scientists are 100% dedicated and committed to the completion of customer projects
Faster implementation of enhanced assays
Higher success rates in clinical trials
Our team can speak the language of both scientists and robot manufacturers
Expertise in wide variety of assay types, including cell-based, vaccine, genomics, proteomics, and ELISA
Robot brand agnostic
ISO-certified with a GLP-development lab

BioSpot

Nanoliter liquid handling workstation

The BioSpot workstation is the most versatile, low volume dispensing system of its kind. Designed as a modular multi-purpose workstation, the BioSpot incorporates the revolutionary PipeJet technology into a fully automated nanoliter dispensing platform. The BioSpot’s wide dispensing range and highly flexible nature allows for precise dispensing onto any type of substrate and can be easily customized to fit every user’s needs.

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The BioSpot introduces unmatched advantages, extreme versatility, and many options for customization. Some features and applications of the BioSpot include:

Up to 12 dispensing channels
Non contact dispensing
Extremely accurate CVs with built-in auto calibration camera
Dispenses in the picoliter, nanoliter, and microliter ranges
Small footprint

Super low dead volumes
Able to dispense into 96, 384, and 1536 well plates, and onto microfluidic slides and cartridges
Built-in camera for fiducial alignment
Zero cross contamination
Able to dispense particles, living cells, viscous fluids, and more

FlexLab

Custom lab automation

FlexLab is a brand new custom automation approach to the discovery lab experience. We’ve coupled the world’s fastest and smartest linear motor conveying system with state-of-the-art robotics and software integration, allowing you to transport and track virtually infinite test samples throughout your entire lab at one time. FlexLab is designed to streamline entire laboratory workflows and drastically reduce sample cycle time from weeks to days, all while giving you the flexibility and freedom to choose your own lab configuration.

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Features & Advantages:

World class, seamless integration from building architecture & infrastructure through automation and software integration
High-speed, intelligent sample handling
Remote lab development including web-based sample ordering, monitoring, and tracking
Global information sharing and access
From station upgrades to 24/7/365 lights out automation

The complete solution cycle from brainstorming through conception, engineering, integrating, and reality
Device integration and/or custom device development
Software integration and/or custom software development
Creation and automation of new processes

LLV

Ultra precision liquid volume verification

Introducing a new product we will be bringing to the lab automation marketplace. This technology is able to measure small volumes in microplate wells at 20 nL liquid volume measurement resolutions and Cv’s of less than 2%. The product will be available as a standalone instrument, or also in a sensor probe form factor that can be mounted right on your robotic liquid handling units. It is non-contact so there is no cross contamination, and it measures the actual liquid in your wells (not a separate calibration liquid).

Volume Measurement

Non-contact
High Resolution
Any liquid
In-line

Performance

Fill height resolution ~ 0.2 µm
Volume resolution ~ 20 nl (96-well)
Inaccuracy < 2%

Indigo

Automated chemical reaction device

Indigo’s intelligent design allows users to easily automate more synthetic chemistry reactions, shorten cycle times, and improve sample integrity. Indigo easily integrates with laboratory robotics or can be used as a standalone automation device for chemists at their workstations.

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Additional features:

Heat, stir, chill, and reflux all on one device
Self-cleaning lid with auto open/close functionality
Adjustable stir rates
Ambient mode for pressure controlled reactions
Accommodates multiple vial sizes

Allows for safe reactions above reflux temperature
Removable vial caps for in-process biopsy
AutoPurge function evacuates each vessel
Wide temperature range (-40 C to 150 C)
Dynamic mode for “in test” vial swap and reagent addition

Harbor

Simple, scalable, plate & sample storage

Treat your samples to the fully customizable Harbor series of sample and plate storage solutions. Harbor sample storage systems are able to accommodate a large variety of sample plates, can interface with your automation robots and software, and can be temperature and atmosphere controlled.

Features included are:

Customizable storage capacity to meet a variety of space constraints Rotary Hotel format or Linear Wall Mount format
Internal robot, external robot, or customer provided robot
Rotating hotels with external robot, or stationary plates with internal robot for sensitive storage
100% traceability through 1D/2D barcode reading, alphanumeric code reading, image scanning, or RFID
Sequential plate load/unload or random plate/location access

Standard inventory retrieval software, or full scheduling software
Standard HMI interface, or web app option for remote access
Ambient or temperature controlled option
Humidity controlled option
Orbital shaking option

PipeJet

Non contact nanoliter dispenser

The PipeJet Nanodispenser Starter Kit includes everything you need to realize your low volume dispensing application. The kit includes a PipeJet dispensing module and the control electronics, as well as the intuitive PipeJet control software. In order to allow for the simplest possible integration of the PipeJet Nanodispenser, the control electronics process external trigger signals. Additionally, the complete PipeJet functionality can be embedded into your system via the provided DLLs.

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Some of the scalable features and benefits of FlexLab include:

Individually programmable droplets from 1 to 70 nL
Dispensing speeds up to 120 Hz
Super low dead volumes
Valve-less technology
Dispensing of live cells

Zero cross contamination
Non contact dispensing
Extremely accurate CVs
Able to dispense into SBS well plates, and onto microfluidic slides and cartridges
Dispensing of aggressive media or viscous fluids

Sierra

Automated sample storage and retrieval system

The Sierra is a rugged high speed storage and retrieval system for pharmaceutical and medical device products. At the heart of the Sierra is a linear motor based robot system delivering ultra-high accelerations with smooth, quiet performance. Cascading hotel racks allow for vast amounts of storage all in a compact footprint.

Some of the scalable features and benefits of FlexLab include:

Full system scan
Updated technology
Standalone capability
Compatible with other robots and conveyer systems
Temperatures as low as -20

Temperatures as high as 80
Integrates production systems via API
Easy to use
Custom options available